Cheesy Meatball Sub Casserole

This Cheesy Meatball Sub Casserole turns the classic sandwich into a hearty, oven-baked meal. Featuring layers of toasted French bread, rich marinara, savory meatballs, and gooey cheese, this comfort food dish is sure to be a hit with the whole family.

Why You’ll Love This Recipe

If you love meatball subs but want something easier to serve for a group or a weeknight dinner, this casserole is the answer. It combines the rich flavors and textures of the traditional sandwich with the ease of a baked dish. The toasted bread soaks up the marinara without going soggy, the cream cheese layer adds unexpected richness, and it’s all topped with plenty of melty mozzarella. It’s a comforting, crowd-pleasing casserole that’s freezer-friendly and easy to prep ahead.

Ingredients

(Tip: You can find the complete list of ingredients and their measurements in the recipe card below.)

• 1 loaf French bread, sliced
• 1 tablespoon olive oil
• 1 teaspoon garlic powder
• 1 (8 oz) package cream cheese, softened
• 1/2 cup mayonnaise
• 1 teaspoon Italian seasoning
• 2 cups shredded mozzarella cheese, divided
• 1/2 cup grated Parmesan cheese
• 1 (28 oz) jar marinara sauce
• 1 (24 oz) bag frozen meatballs, thawed
• Fresh basil or parsley for garnish (optional)

Directions

1. Prepare the Bread
   • Preheat oven to 375°F (190°C).
   • Arrange sliced bread in a single layer on a baking sheet.
   • Brush with olive oil and sprinkle with garlic powder.
   • Toast for 5–7 minutes, until golden and lightly crisped.
2. Mix the Creamy Layer
   • In a medium bowl, combine softened cream cheese, mayonnaise, Italian seasoning, 1 cup mozzarella, and Parmesan.
   • Mix until smooth and evenly blended.
3. Assemble the Casserole
   • Lightly grease a 9×13-inch baking dish.
   • Spread toasted bread slices on the bottom in a single layer.
   • Evenly spread the cream cheese mixture over the bread.
   • Distribute thawed meatballs evenly on top.
   • Pour marinara sauce over the meatballs.
   • Top with remaining 1 cup of mozzarella.
4. Bake
   • Bake uncovered for 30–35 minutes, or until hot and bubbly with golden cheese on top.
5. Garnish and Serve
   • Remove from oven and let sit for 5 minutes.
   • Garnish with fresh basil or parsley if desired.
   • Serve hot.

Servings and timing

Servings: 6 servings
Prep Time: 15 minutes
Cooking Time: 35 minutes
Total Time: 50 minutes
Calories per serving: Approximately 420 kcal

Variations

• Spicy Kick: Add red pepper flakes or sliced jalapeños to the marinara layer for heat.
• Cheese Lover’s Upgrade: Mix in provolone or fontina for more depth of flavor.
• Veggie Boost: Add sautéed bell peppers, mushrooms, or spinach between layers.
• Mini Sub Cups: Assemble individual servings in ramekins for portion control and presentation.
• Low-Carb Version: Substitute bread with thin slices of roasted zucchini or eggplant.

Storage/Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days.
To reheat, cover with foil and warm in a 350°F (175°C) oven for 15–20 minutes, or microwave individual portions for 1–2 minutes.
To freeze, assemble the casserole without baking, wrap tightly, and freeze for up to 2 months. Thaw overnight in the fridge and bake as directed.

FAQs

Can I use homemade meatballs instead of frozen?

Absolutely. Fully cook them before adding to the casserole.

Can I prep this casserole ahead of time?

Yes, you can assemble it up to 24 hours ahead and refrigerate. Bake just before serving.

Is there a substitute for mayonnaise in the cream cheese layer?

You can use sour cream or Greek yogurt for a tangier flavor.

What kind of bread works best?

A crusty French baguette or Italian loaf holds up best when toasted.

Can I use marinara with meat already in it?

Yes, just reduce the number of meatballs slightly to avoid overcrowding.

Is this recipe kid-friendly?

Very much so—it’s cheesy, mild, and familiar in flavor.

Can I add more vegetables?

Yes, sautéed onions, spinach, or bell peppers make great additions.

What if I don’t have Parmesan?

Use Romano or additional mozzarella in its place.

Can this be made gluten-free?

Yes, use gluten-free bread and meatballs, and ensure the sauce is gluten-free.

Can I bake this in a different pan?

You can use a deep square dish, but avoid pans that are too shallow as the layers may overflow.

Conclusion

Cheesy Meatball Sub Casserole is a satisfying, no-fuss dinner that delivers all the comfort of a classic meatball sub in a convenient baked format. Whether you’re feeding a crowd or looking for a hearty make-ahead dish, this layered casserole will become a go-to favorite. With minimal prep and big flavor, it’s the ultimate cozy meal that’s guaranteed to please.

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