If you have ever craved a comforting dish that feels like a warm hug in every bite, then this Creamy Chicken and Spinach Casserole with Cream Cheese Recipe is about to become your new favorite. It brings together tender chicken breasts, fresh spinach, and a luscious cream cheese blend that bakes into a golden, bubbly masterpiece. Whether it’s a weeknight dinner or a special treat for guests, this casserole’s rich creaminess paired with wholesome ingredients will satisfy your taste buds and leave everyone asking for seconds.

Creamy Chicken and Spinach Casserole with Cream Cheese Recipe - Recipe Image

Ingredients You’ll Need

These ingredients may look simple, but each one plays an essential role in creating the irresistible flavor and texture of this casserole. From the juicy chicken to the creamy cheeses and vibrant spinach, you’ll see how every element shines within the dish.

2 large boneless, skinless chicken breasts: The main protein that stays tender and juicy throughout baking.
2 tablespoons olive oil, divided: Adds richness and helps tenderize the chicken while sautéing spinach.
3 cloves garlic, minced: Infuses the marinade with bright, aromatic flavor that lingers in the background.
1 tablespoon Italian seasoning: A fragrant blend that brings herbal depth.
1/2 teaspoon salt: Enhances all the flavors to make every bite pop.
1/2 teaspoon black pepper: Gives a gentle kick and balances the creaminess.
2 cups fresh spinach: Adds a pop of color and a healthy, earthy note.
8 ounces cream cheese, softened: The magic ingredient creating that smooth, creamy base everyone loves.
1 cup shredded mozzarella cheese, divided: Melts perfectly for gooeyness – half mixed in and half for that golden crust.
1/2 cup Parmesan cheese (optional): Adds a savory, nutty edge that elevates the whole dish.

How to Make Creamy Chicken and Spinach Casserole with Cream Cheese Recipe

Step 1: Prepare and Marinate the Chicken

Start by preheating your oven to 400°F and greasing a baking dish. Slice the chicken breasts horizontally to get four thin cutlets and gently pound them for even thickness. Then, whisk together olive oil, garlic, Italian seasoning, salt, and pepper before tossing the chicken cutlets in the mixture. Let the flavors infuse by chilling it in the fridge for 15 to 30 minutes. This step ensures every bite is packed with savory goodness.

Step 2: Wilt the Spinach

Heat a tablespoon of olive oil in a skillet over medium heat and toss in the fresh spinach. Stir frequently until it wilts down, releasing its moisture and bright green color. Removing excess liquid from the spinach is key to keep your casserole from getting soggy. This quick sauté also softens the spinach for an enjoyable texture in the final dish.

Step 3: Make the Cream Cheese Mixture

In a medium bowl, beat the cream cheese until it becomes smooth and creamy. Add the wilted spinach along with half the mozzarella and the Parmesan if using, then mix everything until it forms a luscious, uniform blend. This mixture will become the indulgent layer that makes this casserole special.

Step 4: Cook and Arrange the Chicken

Remove the chicken from the marinade, letting extra drip off. For extra flavor and a bit of crust, quickly sear the cutlets for 1 to 2 minutes on each side in your skillet. Place the chicken in a single layer in your prepared baking dish to create a perfect base for the creamy spinach topping.

Step 5: Assemble and Bake

Spread the spinach and cream cheese mixture over the chicken evenly. Then sprinkle the remaining mozzarella cheese generously on top for that irresistibly golden and bubbly cheese crust. Bake in the preheated oven for 20 to 30 minutes until the chicken is cooked through and the cheese is melted and beautifully browned. Let it rest for a few minutes before serving so the flavors meld perfectly.

How to Serve Creamy Chicken and Spinach Casserole with Cream Cheese Recipe

Garnishes

While this casserole is stunning on its own, a sprinkle of freshly chopped parsley or basil just before serving adds a fresh, herbal brightness that complements the creamy richness. A light dusting of crushed red pepper flakes can also awaken the flavors for those who enjoy a little heat.

Side Dishes

This creamy chicken and spinach casserole pairs wonderfully with simple sides like garlic roasted potatoes, a crisp garden salad, or steamed vegetables to balance its indulgence. For a low-carb option, try serving it alongside cauliflower rice or zucchini noodles for a wholesome, satisfying meal.

Creative Ways to Present

For a special occasion, spoon the casserole into individual ramekins to create charming personal servings. Alternatively, layering this casserole over cooked pasta or rice can turn it into a hearty bake perfect for family-style dinners. Adding toasted breadcrumbs on top before baking gives a delightful crunchy contrast to the creamy interior.

Make Ahead and Storage

Storing Leftovers

Once cooled, store any leftover casserole in an airtight container in the refrigerator for up to 3 days. The flavors actually develop even more, making for an incredible next-day meal. Just make sure to keep it tightly covered to maintain moisture and freshness.

Freezing

This casserole freezes beautifully! Assemble and bake it, then let it cool completely before wrapping it tightly in foil and placing it in a freezer-safe container. It can be frozen for up to 2 months, making it a fantastic make-ahead option for busy nights or unexpected guests.

Reheating

To reheat, thaw overnight in the fridge if frozen. Warm individual servings in the microwave or reheat the entire casserole in a 350°F oven covered with foil for about 15-20 minutes, removing the foil the last few minutes to refresh the golden cheese topping. You’ll have that warm, creamy goodness all over again.

FAQs

Can I use frozen spinach instead of fresh?

Yes! You can substitute frozen spinach but be sure to thaw it completely and squeeze out all excess water to avoid a watery casserole.

Is this recipe low-carb?

Definitely! With chicken, cheese, and spinach as main ingredients, this casserole fits perfectly into a low-carb diet while still being hearty and satisfying.

Can I use other cheeses instead of mozzarella?

Absolutely. Cheeses like cheddar, provolone, or even a bit of feta can add interesting flavors. Just keep in mind how well they melt for the best texture.

How thick should I pound the chicken cutlets?

Aim for about a half-inch thickness so they cook evenly and stay tender without drying out in the oven.

Can I prepare the casserole fully assembled ahead of time?

You can assemble it in advance and refrigerate uncovered before baking. Allow it to come closer to room temperature before popping it in the oven for even cooking.

Final Thoughts

There is something heartwarming about a dish that combines creamy textures, fresh flavors, and an easy assembly like this Creamy Chicken and Spinach Casserole with Cream Cheese Recipe. It brings together simple ingredients in the most delicious way, making it an absolute winner for any meal. I encourage you to roll up your sleeves and try it yourself – it’s a recipe that promises comfort and joy with every bite!

Creamy Chicken and Spinach Casserole with Cream Cheese Recipe